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Studying of Complexes of Zn(II) and Co(II) with Acyclovir (2-amino-9-((2-hydroxyethoxy)methyl)-1,9- dihydro-6H-purine-6-OH)

Studying of Complexes of Zn(II) and Co(II) with Acyclovir (2-amino-9-((2-hydroxyethoxy)methyl)-1,9- dihydro-6H-purine-6-OH)
	© 2024 by IJETT Journal
	Volume-72 Issue-1
	Year of Publication : 2024
	Author : Muratov B.A, Turaev Kh. Kh, Umbarov I.A, Kasimov Sh.A, Nomozov A.K
	DOI : 10.14445/22315381/IJETT-V72I1P120

How to Cite?

Muratov B.A, Turaev Kh. Kh, Umbarov I.A, Kasimov Sh.A, Nomozov A.K, "Studying of Complexes of Zn(II) and Co(II) with Acyclovir (2-amino-9-((2-hydroxyethoxy)methyl)-1,9- dihydro-6H-purine-6-OH)," International Journal of Engineering Trends and Technology, vol. 72, no. 1, pp. 202-208, 2024. Crossref, https://doi.org/10.14445/22315381/IJETT-V72I1P120

Abstract
In this paper, the optimal conditions for the synthesis of complex compounds of zinc (II) and cobalt (II) metals [(C8H10N5O3)2Zn] and [(C8H10N5O3)2Co] with aciclovir, one of the drugs used against viruses, were determined. In this case, 0.1 M ZnSO4 and 0.1 M CoSO4 solutions and 0.2 M, 0.4 M and 0.6 molar ethanol solutions of aciclovir were used. During synthesis, the temperature was 50-60 0C, and the mixing duration was two hours. In addition, all reactions were carried out at pH=5. Physico-chemical properties of obtained complex compounds were analyzed by methods such as IR-spectra, DTA and TGA, and Scanning Electron Microscope.

Keywords
Acyclovir, Zinc sulfate, Cobalt sulfate, Ethanol, Scanning Electron Microscope, IR-spectra.

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