Computer-Aided Detection (CAD) system for the Detection and Classification of Pulmonary Nodules in Lung Cancer using CT images
Computer-Aided Detection (CAD) system for the Detection and Classification of Pulmonary Nodules in Lung Cancer using CT images |
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© 2023 by IJETT Journal | ||
Volume-71 Issue-1 |
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Year of Publication : 2023 | ||
Author : Aparna M. Harale, Vinayak K. Bairagi |
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DOI : 10.14445/22315381/IJETT-V71I1P204 |
How to Cite?
Aparna M. Harale, Vinayak K. Bairagi, "Computer-Aided Detection (CAD) system for the Detection and Classification of Pulmonary Nodules in Lung Cancer using CT images," International Journal of Engineering Trends and Technology, vol. 71, no. 1, pp. 31-40, 2023. Crossref, https://doi.org/10.14445/22315381/IJETT-V71I1P204
Abstract
Lung cancer is one type of serious disorder around the globe. In comparison to other forms of cancer in both males and females, lung cancer records the highest number of cancer-related deaths. Pulmonary nodules are blob-like shapes that are potential manifestations of lung cancer and diameter between 3 to 30 mm. correct examinations of nodules are required for the lung cancer diagnosis and the subsequent treatment schedule. Lung cancer screening can significantly reduce the death rate. Novice radiologists rely on professional specialists to study lung CT images. The primary bottleneck for such a traditional learning system is a lack of time from professional radiologists. Hence, there is a requirement for the development of an Automatic Computer Aided Detection system (CAD) to assist radiologists and the analysis of lung cancer. Due to poor image quality that interferes with the segmentation process, traditional lung cancer prediction approaches could not maintain accuracy. In order to predict lung cancer, novel, improved image processing and machine learning technique is presented in this study. This paper aims to develop an Automatic CAD system to diagnose lung cancer. The Lung Image Database Consortium (LIDC) CT image was used. The detection of nodules is done using UNET architecture, and its malignancy is decided with an ensemble of three classifiers, SVM, KNN and LR are examined using Python. LR gives the highest accuracy, 97.92%. Performance check of different classifiers using Accuracy, Sensitivity, Specificity, Precision, and F1 Score. The ensemble of three classifiers model detects and classifies lung nodules with an accuracy of 83%.
Keywords
Computer tomography, Computer-aided diagnosis, Lung cancer, Nodule, Nodule detection.
References
[1] Cancer Facts and Figure 2022 by American Cancer Society. [Online]. Available : http://www.cancer.org
[2] Ashis Kumar Dhara, Sudipta Mukhopadhyay, and Niranjan Khandelwal, “Computer-Aided Detection and Analysis of Pulmonary Nodule from CT Images: A Survey,” IETE Technical Review, vol. 29, no. 4, pp. 265-275, 2012. Crossref, https://doi.org/10.4103/0256-4602.101306
[3] Early Lung Cancer Action Program (ELCAP), [Online]. Available: http://www.via.cornell.edu/lungdb.html.[last cited on 2022].
[4] Lung Imaging Database Consortium (LIDC), 2022. [Online]. Available: https://imaging.nci.nih.gov/ncia/login.jsf./ http://www.cancerimagingarchive.net
[5] Medical Image Database, Medpix, 2022. [Online]. Available: http://rad.usuhs.edu/medpixlindex.html.
[6] Martin Dolejsi et al., “The Lung TIME: Annotated Lung Nodule Dataset and Nodule Detection Framework,” Proceedings Medical Imaging 2009: Computer-Aided Diagnosis, vol. 7260, 2009. Crossref, https://doi.org/10.1117/12.811645
[7] Aparna Rajesh Lokhande, and Dr. Vinayak K. Bairagi, “Computer Aided Detection of Lung Cancer Pulmonary Nodules From CT Images: A Recent Survey,” International Journal of Advanced Information Science and Technology, vol. 6, no. 6, pp. 20-32, 2017.
[8] Salsabil A. El-Regaily et al., “Survey of Computer Aided Detection Systems for Lung Cancer in Computed Tomography,” Current Medical Imaging Reviews, vol. 14, no. 1, pp. 3-18, 2018. Crossref, http://dx.doi.org/10.2174/1573405613666170602123329
[9] P. Mohamed Shakeel et al., “Automatic Detection of Lung Cancer From Biomedical Data Set Using Discrete AdaBoost Optimized Ensemble Learning Generalized Neural Networks,” Neural Computing and Applications, vol. 32, pp. 777-790, 2020. Crossref, https://doi.org/10.1007/s00521-018-03972-2
[10] P. Mohamed Shakeel, M. A. Burhanuddin, and Mohammad Ishak Desa, “Automatic Lung Cancer Detection from CT Image Using Improved Deep Neural Network and Ensemble Classifier,” Neural Computing and Applications, vol. 34, pp. 9579–9592, 2022. Crossref, https://doi.org/10.1007/s00521-020-04842-6
[11] Ummadi Janardhan Reddy et al., “Recognition of Lung Cancer Using Machine Learning Mechanisms with Fuzzy Neural Networks,” Traitement Du Signal, vol. 36, no. 1, pp. 87-91, 2019.
[12] Suren Makaju et al., “Lung Cancer Detection Using CT Scan Images,” Procedia Computer Science, vol. 125, pp. 107-114, 2018. Crossref, https://doi.org/10.1016/j.procs.2017.12.016
[13] Xuechen Li, “Multi-Resolution Convolutional Networks for Chest X-Ray Radiograph-Based Lung Nodule Detection,” Artificial Intelligence in Medicine, vol. 103, 2020. Crossref, https://doi.org/10.1016/j.artmed.2019.101744
[14] Ahmed Soliman et al., “Accurate Lungs Segmentation on CT Chest Images by Adaptive Appearance-Guided Shape Modeling,” IEEE Transactions on Medical Imaging, vol. 36, no. 1, pp. 263–276, 2017.
[15] Pedro Pedrosa Rebouças Filho et al., “Novel and Powerful 3D Adaptive Crisp Active Contour Method Applied in the Segmentation of CT Lung Images,” Medical Image Analysis, vol. 35, pp. 503–516, 2017. Crossref, https://doi.org/10.1016/j.media.2016.09.002
[16] Z. Shi et al., “Many is Better Than One: An Integration of Multiple Simple Strategies for Accurate Lung Segmentation in CT Images,” Biomed Research International, pp. 1-13, 2016. Crossref, https://doi.org/10.1155/2016/1480423
[17] Abhir Bhandary et al., “Deep-Learning Framework to Detect Lung Abnormality–A Study with Chest X-Ray and Lung CT Scan Images,” Pattern Recognition Letters, vol. 129, pp. 271-278, 2020. Crossref, https://doi.org/10.1016/j.patrec.2019.11.013
[18] Siddharth Bhatia, Yash Sinha, and Lavika Goel, “Lung Cancer Detection: A Deep Learning Approach,” Soft Computing for Problem Solving, Springer, vol. 817, pp. 699-705, 2019. Crossref, https://doi.org/10.1007/978-981-13-1595-4_55
[19] João Rodrigo Ferreirada Silva Sousa et al., “Methodology for Automatic Detection of Lung Nodules in Computerized Tomography Images,” Computer Methods and Programs in Biomedicine, vol. 98, no. 1, pp. 1-14, 2018. Crossref, https://doi.org/10.1016/j.cmpb.2009.07.006
[20] O. Obulesu et al., “Adaptive Diagnosis of Lung Cancer By Deep Learning Classification Using Wilcoxon Gain and Generator,” Hindawi Journal of Healthcare Engineering, vol. 2021, 2021. Crossref, https://doi.org/10.1155/2021/5912051
[21] Wenfa Jiang et al., “Application of Deep Learning in Lung Cancer Imaging Diagnosis,” Hindawi Journal of Healthcare Engineering, vol. 3, 2022. Crossref, https://doi.org/10.1155/2022/6107940
[22] Nasrullah Nasrullah et al., “Automated Lung Nodule Detection and Classification Using Deep Learning Combined with Multiple Strategies,” Sensors, vol. 19, no. 17, p. 3722, 2022. Crossref, https://doi.org/10.3390/s19173722
[23] Ebanesar.C et al., "Computer Aided System for Automated Heterogeneous Cancer Recognition Using Google Cloud Platform," SSRG International Journal of Computer Science and Engineering, vol. 5, no. 5, pp. 11-16, 2018. Crossref, https://doi.org/10.14445/23488387/ijcse-v5i5p103
[24] Ashis Kumar Dhara et al., “A Combination of Shape and Texture Features for Classification of Pulmonary Nodules in Lung CT Images,” Journal of Digital Imaging, vol. 29, no. 4, pp. 466-475, 2016. Crossref, https://doi.org/10.1007/s10278-015-9857-6
[25] V. Shalini, and K. S. Angel Viji, "Integration of Convolutional Features and Residual Neural Network for the Detection and Classification of Leukemia From Blood Smear Images," International Journal of Engineering Trends and Technology, vol. 70, no. 9, pp. 176-184, 2022. Crossref, https://doi.org/10.14445/22315381/ijett-v70i9p218
[26] Ivan William Harsono et al., “Lung Nodule Detection and Classification From Thorax CT-Scan Using Retinanet with Transfer Learning,” Journal of King Saud University – Computer and Information Sciences, Elsevier, vol. 34, no. 4, pp. 567-577, 2022. Crossref, https://doi.org/10.1016/j.jksuci.2020.03.013
[27] Akila Victor et al., "Detection and Classification of Breast Cancer Using Machine Learning Techniques for Ultrasound Images," International Journal of Engineering Trends and Technology, vol. 70, no. 3, pp. 170-178, 2022. Crossref, https://doi.org/10.14445/22315381/ijett-v70i3p219
[28] Ruchika, and Archna Sharma, “CAD Implementation for Detection of Lung Cancerous Nodules,” International Journal of Advanced Research in Computer Science and Software Engineering, vol. 6, no. 4, pp. 804-806, 2016.